Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia? Review of Key Points Toward an Accurate Clinical and Neuropsychological Diagnosis

AUTORES	Musa G, Slachevsky A, Muñoz-Neira C, Méndez C, Villagra R, González-Billault C, Ibáñez A, Hornberger M, Lillo P.
	2019
JOURNAL	J Alzheimers Dis.
VOLUMEN	2019 Dec 26. doi: 10.3233/JAD-190924. PubMed PMID: 31884475.
ABSTRACT	Alzheimer’s disease (AD) and frontotemporal dementia (FTD) are the most common neurodegenerative early-onset dementias. Despite the fact that both conditions have a very distinctive clinical pattern, they present with an overlap in their cognitive and behavioral features that may lead to misdiagnosis or delay in diagnosis. The current review intends to summarize briefly the main differences at the clinical, neuropsychological, and behavioral levels, in an attempt to suggest which aspects would facilitate an adequate diagnosis in a clinical setting, especially in Latin American and low- and middle-income countries, where the resources needed for a differential diagnosis (such as MRI or biomarkers) are not always available. A timely diagnosis of AD and FTD have significant implications for the medical management and quality of life of patients and careers.
	En este trabajo abordamos las diferencias a nivel clínico, neuropsicológico y conductual de la enfermedad de Alzheimer y la demencia frontotemporal, con un foco especialmente relevante para países latinoamericanos y de bajos/medianos ingresos, donde los recursos de resonancia magnética o biomarcadores no siempre están disponibles.

Alzheimer’s Disease or Behavioral Variant Frontotemporal Dementia? Review of Key Points Toward an Accurate Clinical and Neuropsychological Diagnosis