Cognitive but not affective Theory of Mind (ToM) deficits in mild Relapsing Remitting Multiple Sclerosis (RRMS).
| Autores | Roca M, Manes F, Gleichgerrcht E, Ibanez A, González Toledo ME, Marenco V, Bruno D, Torralva T, Sinay V. |
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| Año | 2014 |
| Journal | Roca M, Manes F, Gleichgerrcht E, Ibanez A, González Toledo ME, Marenco V, Bruno D, Torralva T, Sinay V. |
| Volumen | 27:25-30 |
| Abstract | Objective: We studied theory of mind (ToM) in patients withmild relapsing-remitting multiple sclerosis (MS), seeking possibledissociations between its 2 components: cognitive ToM (theability to infer others intentions) and affective ToM (the abilityto infer others emotional states). We analyzed the relationshipof ToM to executive function, depression, and fatigue. Background: Dissociations between cognitive and affective ToMhave been found in several neurologic and neuropsychiatricdiseases. Most ToM studies in patients with MS have showngeneral ToM deficits but have not analyzed the cognitive andaffective aspects individually. Methods: We used the Faux Pas test of ToM and tests of executivefunction to assess 18 patients with mild relapsing-remittingMS and 16 control participants. Results: Our patients showed deficits in cognitive ToM, but theiraffective ToM seemed to be spared. Their cognitive ToM deficitswere not related to executive dysfunction, depression, or fatigue. Conclusions: Our study is the first differential analysis showingcognitive but not affective ToM deficits in mild relapsing-remittingMS. Further research is needed to determine the exactnature and the real impact of these deficits, and to establish theirrelationship with the neuropathology and progression of MS. |
| Otra información | En esta investigación los autores demuestran afectación de la habilidad de inferir pensamientos pero no de la habilidad de inferir sentimientos en pacientes con esclerosis múltiple. La misma tiene importantes implicancias para la clínica y la investigación de esta patología |